Rui Manuel Amaro Pinto
Rui Pinto is a Professor of Pharmacology at the Department of Pharmacy, Pharmacology and Health Technologies of the Faculty of Pharmacy – University of Lisbon. He is Pharmacist Specialist in clinical analysis (AC) and in human genetics (GH) by the Order of Pharmacists (OF). With the background in Pharmacology and Laboratory Medicine, he is interested in the research areas related to the identification and validation of biomarkers associated with the pathophysiology of diseases using animal models. His background in the area related to the drug-receptor interaction has allowed him to develop experimental work in the field of molecular pharmacology and inflammation. He leads a line of research that he began to develop in 2011 related to the pharmacological modulation of inflammation associated with inflammatory bowel disease – from animal model study to clinical trial. The research areas in which he is involved already allow the publication of more than 110 full papers in international peer-reviewed journals with a total number of citations (web of science): 1393 and acts as reviewer of international peer-reviewed journals in the area of Pharmacology and Laboratory Medicine. In the Health Regulatory area, he is a Pre-Clinical Pharmacology and Toxicology Expert Assessor for the Medicines Evaluation Committee at INFARMED (National Authority of Medicines and Health Products). He is also a Toxicological and Pharmaceutical Expert Assessor for DGAV (Directorate General for Food and Veterinary). He is Chairman of the Board of the College of Specialties in AC and GH of the OF (2016-2021); Member of the Board of the Order of Pharmacists and founding partner of the European Union of Pharmacists Specialists in AC and GH (EUPLMG).
Projetos
Projetos
2015 - Presente. IBD Inflammatory Bowel Disease.
Produções
Vanessa Mateus; João Rocha; Helder Mota-Filipe; Bruno Sepodes; Rui Pinto. 2018. "Hemin reduces inflammation associated with TNBS-induced colitis". Clinical and Experimental Gastroenterology. https://doi.org/10.2147/CEG.S166197
Carlos Cardoso; Joana Paiva Martinho; Paula A. Lopes; Susana Martins; Jorge Correia; Cláudia Afonso; Francisco J. Alarcón; et al. 2018. "Stearidonic acid combined with alpha-linolenic acid improves lipemic and neurological markers in a rat model subject to a hypercaloric diet". Prostaglandins, Leukotrienes and Essential Fatty Acids, 135: 137-146. https://doi.org/10.1016/j.plefa.2018.07.010
Inês Bártolo; Philippe A. Gallay; Ana Rita Diniz; Pedro Borrego; João Pedro Ferreira; Maria Rosário Bronze; Helena Barroso; et al. 2018. "Evaluation of the fusion inhibitor P3 peptide as a potential microbicide to prevent HIV transmission in women". PLOS ONE, 13 (4): e0195744-e0195744. https://doi.org/10.1371/journal.pone.0195744
Madeira, Marta S; Rolo, Eva A; Lopes, Paula A; Ramos, Denis A; Alfaia, Cristina M; Pires, Virginia Mr; Martins, Susana V; Pinto, Rui Ma; Prates, Jose Am. 2017. "Betaine and arginine supplementation of low protein diets improves plasma lipids but does not affect hepatic fatty acid composition and related gene expression profiling in pigs.". Journal of the science of food and agriculture. https://doi.org/10.1002/jsfa.8504
Madeira, M.S.M.S.; Rolo, E.S.A.; Pires, V.M.R.; Alfaia, C.M.R.P.M.; Coelho, D.F.M.; Lopes, P.A.A.B.; Martins, S.I.V.; Pinto, R.M.A.; Prates, J.A.M.. 2017. "Arginine supplementation modulates pig plasma lipids, but not hepatic fatty acids, depending on dietary protein level with or without leucine". BMC Veterinary Research, 13 (1). https://doi.org/10.1186/s12917-017-1063-y
Aguiar, Patricio; Azevedo, Olga; Pinto, Rui; Marino, Jacira; Cardoso, Carlos; Ducla Soares, Jose Luis; Hughes, Derralynn. 2017. "Increase synthesis of collagen type I: an early event in Fabry cardiomyopathy. New biomarkers?". Molecular Genetics and Metabolism, 120 (1-2): S17-S18. https://doi.org/10.1016/j.ymgme.2016.11.012
Direito, R.; Lima, A.; Rocha, J.; Ferreira, R.B.; Mota, J.; Rebelo, P.; Fernandes, A.; et al. 2017. "Dyospiros kaki phenolics inhibit colitis and colon cancer cell proliferation, but not gelatinase activities". Journal of Nutritional Biochemistry, 46: 100-108. https://doi.org/10.1016/j.jnutbio.2017.03.002
Mateus, V.; Rocha, J.; Alves, P.; Mota-Filipe, H.; Sepodes, B.; Pinto, R.. 2017. "Thiadiazolidinone-8 Ameliorates Inflammation Associated with Experimental Colitis in Mice". Pharmacology, 35-42. https://doi.org/10.1159/000471808
Lopes, P.A.; Bandarra, N.M.; Martins, S.V.; Martinho, J.; Alfaia, C.M.; Madeira, M.S.; Cardoso, C.; et al. 2017. "Markers of neuroprotection of combined EPA and DHA provided by fish oil are higher than those of EPA (Nannochloropsis) and DHA (Schizochytrium) from microalgae oils in Wistar rats". Nutrition and Metabolism, 14 (1). https://doi.org/10.1186/s12986-017-0218-y
De Mello-Sampayo, C.; Paterna, A.; Polizzi, A.; Duarte, D.; Batista, I.; Pinto, R.; Gonçalves, P.; et al. 2017. "Evaluation of marine microalga Diacronema vlkianum biomass fatty acid assimilation in Wistar rats". Molecules, 22 (7). https://doi.org/10.3390/molecules22071097
Aguiar, P.; Azevedo, O.; Pinto, R.; Marino, J.; Baker, R.; Cardoso, C.; Ducla Soares, J.L.; Hughes, D.. 2017. "New biomarkers defining a novel early stage of Fabry nephropathy: A diagnostic test study". Molecular Genetics and Metabolism, 121 (2): 162-169. https://doi.org/10.1016/j.ymgme.2017.05.007
Bandarra, N.M.; Lopes, P.A.; Martins, S.V.; Ferreira, J.; Alfaia, C.M.; Rolo, E.A.; Correia, J.J.; et al. 2016. "Docosahexaenoic acid at the sn-2 position of structured triacylglycerols improved n-3 polyunsaturated fatty acid assimilation in tissues of hamsters". Nutrition Research, 36 (5): 452-463. https://doi.org/10.1016/j.nutres.2015.12.015
Aguiar, Patricio; Pinto, Rui; Azevedo, Olga; Marino, Jacira; Baker, Rob; Cardoso, Carlos; Ducla Soares, Jose Luis; Hughes, Derralynn. 2016. "Urinary type IV collagen: Better than albuminuria to identify incipient Fabry nephropathy". Molecular Genetics and Metabolism, 117 (2): S16-S16. https://doi.org/10.1016/j.ymgme.2015.12.165
Madeira, M.S.; Pires, V.M.R.; Alfaia, C.M.; Lopes, P.A.; Martins, S.V.; Pinto, R.M.A.; Prates, J.A.M.. 2016. "Restriction of dietary protein does not promote hepatic lipogenesis in lean or fatty pigs". British Journal of Nutrition, 115 (8): 1339-1351. https://doi.org/10.1017/S0007114516000453
Mateus, V.; Rocha, J.; Alves, P.; Mota-Filipe, H.; Sepodes, B.; Pinto, R.M.A.. 2016. "Anti-Inflammatory Effect of Erythropoietin in the TNBS-induced Colitis". Basic and Clinical Pharmacology and Toxicology. https://doi.org/10.1111/bcpt.12663
de Jesus Gaffney, V.; Mota-Filipe, H.; Pinto, R.A.; Thiemermann, C.; Loureiro, M.; Cardoso, V.V.; Benoliel, M.J.; Almeida, C.M.M.. 2016. "Chemical and biochemical characterization and in vivo safety evaluation of pharmaceuticals in drinking water". Environmental Toxicology and Chemistry, 35 (11): 2674-2682. https://doi.org/10.1002/etc.3451
Rocha, J.; Eduardo-Figueira, M.; Barateiro, A.; Fernandes, A.; Brites, D.; Bronze, R.; Duarte, C.M.; et al. 2015. "Anti-inflammatory effect of rosmarinic acid and an extract of rosmarinus officinalis in rat models of local and systemic inflammation". Basic and Clinical Pharmacology and Toxicology, 116 (5): 398-413. https://doi.org/10.1111/bcpt.12335
Esteban, M.; Schindler, B.K.; Jiménez, J.A.; Koch, H.M.; Angerer, J.; Rosado, M.; Gómez, S.; et al. 2015. "Mercury analysis in hair: Comparability and quality assessment within the transnational COPHES/DEMOCOPHES project". Environmental Research, 141: 24-30. https://doi.org/10.1016/j.envres.2014.11.014
Rocha, J.; Figueira, M.-E.; Barateiro, A.; Fernandes, A.; Brites, D.; Pinto, R.; Freitas, M.; et al. 2015. "Inhibition of glycogen synthase kinase-3ß attenuates organ injury and dysfunction associated with liver ischemia-reperfusion and thermal injury in the rat". Shock, 43 (4): 369-378. https://doi.org/10.1097/SHK.0000000000000298
Lopes, P.A.; Costa, A.S.H.; Costa, P.; Pires, V.M.R.; Madeira, M.S.; Achega, F.; Pinto, R.M.A.; Prates, J.A.M.. 2014. "Contrasting cellularity on fat deposition in the subcutaneous adipose tissue and longissimus lumborum muscle from lean and fat pigs under dietary protein reduction". Animal, 8 (4): 629-637. https://doi.org/10.1017/S1751731114000160
Rocha, J.; Eduardo-Figueira, M.; Barateiro, A.; Fernandes, A.; Brites, D.; Pinto, R.; Freitas, M.; et al. 2014. "Erythropoietin Reduces Acute Lung Injury and Multiple Organ Failure/Dysfunction Associated to a Scald-Burn Inflammatory Injury in the Rat". Inflammation, 38 (1): 312-326. https://doi.org/10.1007/s10753-014-0035-7
da Costa, A.S.H.; Bessa, R.J.B.; Pires, V.M.R.; Rolo, E.A.; Pinto, R.M.A.; Andrade Fontes, C.M.G.; Prates, J.A.M.. 2014. "Is hepatic lipid metabolism of beef cattle influenced by breed and dietary silage level?". BMC Veterinary Research, 10. https://doi.org/10.1186/1746-6148-10-65
Ratilal, B.O.; Rocha, J.P.F.; Fernandes, A.M.A.; Arroja, M.M.C.; Barateiro, A.P.; Brites, D.M.T.O.; Pinto, R.M.A.; Sepodes, B.M.N.; Mota-Filipe, H.D.. 2014. "TDZD-8 pre-treatment in transient middle cerebral artery occlusion". Biomedicine and Aging Pathology, 4 (4): 361-367. https://doi.org/10.1016/j.biomag.2014.07.005
Ratilal, B.O.; Arroja, M.M.C.; Rocha, J.P.F.; Fernandes, A.M.A.; Barateiro, A.P.; Brites, D.M.T.O.; Pinto, R.M.A.; Sepodes, B.M.N.; Mota-Filipe, H.D.. 2014. "Neuroprotective effects of erythropoietin pretreatment in a rodent model of transient middle cerebral artery occlusion: Laboratory investigation". Journal of Neurosurgery, 121 (1): 55-62. https://doi.org/10.3171/2014.2.JNS132197
Rodrigues, P.O.; Martins, S.V.; Lopes, P.A.; Ramos, C.; Miguéis, S.; Alfaia, C.M.; Pinto, R.M.A.; et al. 2014. "Influence of feeding graded levels of canned sardines on the inflammatory markers and tissue fatty acid composition of Wistar rats". British Journal of Nutrition, 112 (3): 309-319. https://doi.org/10.1017/S0007114514000853
Ribeiro, T.; Lordelo, M.M.; Costa, P.; Alves, S.P.; Benevides, W.S.; Bessa, R.J.B.; Lemos, J.P.C.; et al. 2014. "Effect of reduced dietary protein and supplementation with a docosahexaenoic acid product on broiler performance and meat quality". British Poultry Science, 55 (6): 752-765. https://doi.org/10.1080/00071668.2014.971222
Mascarenhas-Melo, F.; Palavra, F.; Marado, D.; Sereno, J.; Teixeira-Lemos, E.; Freitas, I.; Isabel-Mendonça, M.; et al. 2013. "Emergent biomarkers of residual cardiovascular risk in patients with low HDL-c and/or high triglycerides and average LDL-c concentrations: Focus on HDL subpopulations, oxidized LDL, adiponectin, and uric acid". The Scientific World Journal, 2013. https://doi.org/10.1155/2013/387849
de Mello-Sampayo, C.; Corvo, M.L.; Mendes, R.; Duarte, D.; Lucas, J.; Pinto, R.; Batista, A.P.; et al. 2013. "Insights on the safety of carotenogenic Chlorella vulgaris in rodents". Algal Research, 2 (4): 409-415. https://doi.org/10.1016/j.algal.2013.07.005
Mascarenhas-Melo, F.; Sereno, J.; Teixeira-Lemos, E.; Marado, D.; Palavra, F.; Pinto, R.; Rocha-Pereira, P.; Teixeira, F.; Reis, F.. 2013. "Implication of low HDL-c levels in patients with average LDL-c levels: A focus on oxidized LDL, large HDL subpopulation, and adiponectin". Mediators of Inflammation, 2013. https://doi.org/10.1155/2013/612038
Mascarenhas-Melo, F.; Marado, D.; Palavra, F.; Sereno, J.; Coelho, T.; Pinto, R.; Teixeira-Lemos, E.; Teixeira, F.; Reis, F.. 2013. "Diabetes abrogates sex differences and aggravates cardiometabolic risk in postmenopausal women". Cardiovascular Diabetology, 12 (1). https://doi.org/10.1186/1475-2840-12-61
García-Lestón, J.; Roma-Torres, J.; Vilares, M.; Pinto, R.; Prista, J.; Teixeira, J.P.; Mayan, O.; et al. 2012. "Genotoxic effects of occupational exposure to lead and influence of polymorphisms in genes involved in lead toxicokinetics and in DNA repair". Environment International, 43 (1): 29-36. https://doi.org/10.1016/j.envint.2012.03.001
Costa, A.S.H.; Lopes, P.A.; Estevão, M.; Martins, S.V.; Alves, S.P.; Pinto, R.M.A.; Pissarra, H.; et al. 2012. "Contrasting cellularity and fatty acid composition in fat depots from Alentejana and Barrosã bovine breeds fed high and low forage diets". International Journal of Biological Sciences, 8 (2): 214-227. http://www.scopus.com/inward/record.url?eid=2-s2.0-84856165348&partnerID=MN8TOARS
Teixeira De Lemos, E.; Pinto, R.; Oliveira, J.; Garrido, P.; Sereno, J.; Mascarenhas-Melo, F.; Páscoa-Pinheiro, J.; Teixeira, F.; Reis, F.. 2011. "Differential effects of acute (extenuating) and chronic (training) exercise on inflammation and oxidative stress status in an animal model of type 2 diabetes mellitus". Mediators of Inflammation, 2011. https://doi.org/10.1155/2011/253061
Parada, B.; Reis, F.; Figueiredo, A.; Nunes, P.; Teixeira-Lemos, E.; Garrido, P.; Sereno, J.; et al. 2011. "Inhibition of bladder tumour growth by sirolimus in an experimental carcinogenesis model". BJU International, 107 (1): 135-143. https://doi.org/10.1111/j.1464-410X.2010.09326.x
García-Lestón, J.; Roma-Torres, J.; Vilares, M.; Pinto, R.; Cunha, L.M.; Prista, J.; Teixeira, J.P.; et al. 2011. "Biomonitoring of a population of Portuguese workers exposed to lead". Mutation Research - Genetic Toxicology and Environmental Mutagenesis, 721 (1): 81-88. https://doi.org/10.1016/j.mrgentox.2011.01.001
Rauter, A.P.; Martins, A.; Borges, C.; Mota-Filipe, H.; Pinto, R.; Sepodes, B.; Justino, J.. 2010. "Antihyperglycaemic and protective effects of flavonoids on streptozotocin-induced diabetic rats". Phytotherapy Research, 24 (SUPPL. 2). https://doi.org/10.1002/ptr.3017
Sereno, J.; Parada, B.; Reis, F.; Cunha, F.X.; Teixeira-Lemos, E.; Garrido, P.; Pinto, R.; et al. 2010. "Preventive but Not curative efficacy of celecoxib on bladder carcinogenesis in a rat model". Mediators of Inflammation, 2010. https://doi.org/10.1155/2010/380937
Garrido, P.; Reis, F.; Costa, E.; Almeida, A.; Parada, B.; Teixeira-Lemos, E.; Santos, P.; et al. 2010. "Effect of recombinant human erythropoietin in a rat model of moderate chronic renal failure - focus on inflammation, oxidative stress and function/renoprotection". Open Drug Discovery Journal, 2 (SPEC. ISS.): 25-32. https://doi.org/10.2174/1877381801002020025
Reis, F.; Ferreira, L.; Teixeira-De-Lemos, E.; Pinto, F.; Parada, B.; Mega, C.; Vala, H.; et al. 2010. "Effects of sitagliptin treatment on dysmetabolism, inflammation, and oxidative stress in an animal model of type 2 diabetes (ZDF rat)". Mediators of Inflammation, 2010. https://doi.org/10.1155/2010/592760
Teixeira, A.M.; Garrido, P.; Santos, P.; Alves, R.; Parada, B.; Costa, E.; Almeida, A.; et al. 2010. "Recombinant human erythropoietin treatment protects the cardio-renal axis in a model of moderate chronic renal failure". Renal Failure, 32 (9): 1073-1080. https://doi.org/10.3109/0886022X.2010.509897
Rauter, A.P.; Martins, A.; Borges, C.; Mota-Filipe, H.; Pinto, R.; Sepodes, B.; Justino, J.. 2010. "Antihyperglycaemic and protective effects of flavonoids on streptozotocin-induced diabetic rats (Phytotherapy Research (2010) 24, Supplement 2 DOI: 10.1002/ptr.3017)". Phytotherapy Research, 24 (SUPPL. 2). https://doi.org/10.1002/ptr.3253
Martins, S.V.; Lopes, P.A.; Alfaia, C.M.; Rodrigues, P.O.; Alves, S.P.; Pinto, R.M.A.; Castro, M.F.; Bessa, R.J.B.; Prates, J.A.M.. 2010. "Serum adipokine profile and fatty acid composition of adipose tissues are affected by conjugated linoleic acid and saturated fat diets in obese Zucker rats". British Journal of Nutrition, 103 (6): 869-878. https://doi.org/10.1017/S000711450999256X
Bignotto, L.; Rocha, J.; Sepodes, B.; Eduardo-Figueira, M.; Pinto, R.; Chaud, M.; De Carvalho, J.; Moreno Jr., H.; Mota-Filipe, H.. 2009. "Anti-inflammatory effect of lycopene on carrageenan-induced paw oedema and hepatic ischaemia-reperfusion in the rat". British Journal of Nutrition, 102 (1): 126-133. https://doi.org/10.1017/S0007114508137886
Parada, B.; Sereno, J.; Reis, F.; Teixeira-Lemos, E.; Garrido, P.; Pinto, A.F.; Cunha, M.F.; et al. 2009. "Anti-inflammatory, anti-proliferative and antioxidant profiles of selective cyclooxygenase-2 inhibition as chemoprevention for rat bladder carcinogenesis". Cancer Biology and Therapy, 8 (17): 1615-1622. https://doi.org/10.4161/cbt.8.17.9199
Teixeira de Lemos, E.; Reis, F.; Baptista, S.; Pinto, R.; Sepodes, B.; Vala, H.; Rocha-Pereira, P.; et al. 2009. "Exercise training decreases proinflammatory profile in Zucker diabetic (type 2) fatty rats". Nutrition, 25 (3): 330-339. https://doi.org/10.1016/j.nut.2008.08.014
Rauter, A.P.; Martins, A.; Lopes, R.; Ferreira, J.; Serralheiro, L.M.; Araújo, M.-E.; Borges, C.; et al. 2009. "Bioactivity studies and chemical profile of the antidiabetic plant Genista tenera". Journal of Ethnopharmacology, 122 (2): 384-393. https://doi.org/10.1016/j.jep.2008.10.011
Garrido, P.; Reis, F.; Costa, E.; Teixeira-Lemos, E.; Parada, B.; Alves, R.; Piloto, N.; et al. 2009. "Characterization of a rat model of moderate chronic renal failurefocus on hematological, biochemical, and cardio-renal profiles". Renal Failure, 31 (9): 833-842. https://doi.org/10.3109/08860220903151435
Piloto, N.; Teixeira, H.M.; Teixeira-Lemos, E.; Parada, B.; Garrido, P.; Sereno, J.; Pinto, R.; et al. 2009. "Erythropoietin promotes deleterious cardiovascular effects and mortality risk in a rat model of chronic sports doping". Cardiovascular Toxicology, 9 (4): 201-210. https://doi.org/10.1007/s12012-009-9054-2
Lopes, P.A.; Martins, S.V.; Pinho, M.S.; Alfaia, C.M.; Fontes, C.M.G.A.; Rodrigues, P.O.; Morais, G.S.L.; et al. 2008. "Diet supplementation with the cis-9,trans-11 conjugated linoleic acid isomer affects the size of adipocytes in Wistar rats". Nutrition Research, 28 (7): 480-486. https://doi.org/10.1016/j.nutres.2008.04.002
Maio, R.; Sepodes, B.; Figueiredo, N.; Pinto, R.; McDonald, M.; Thiermermann, C.; Costa, P.; Mota-Filipe, H.. 2007. "Effects of Diethyldithiocarbamate (DETC) on Liver Injury Induced by Ischemia-Reperfusion in Rats". Transplantation Proceedings, 39 (2): 365-368. https://doi.org/10.1016/j.transproceed.2007.01.004
De Lemos, E.T.; Reis, F.; Baptista, S.; Pinto, R.; Sepodes, B.; Vala, H.; Rocha-Pereira, P.; Silva, A.S.; Teixeira, F.. 2007. "Exercise training is associated with improved levels of C-reactive protein and adiponectin in ZDF (type 2) diabetic rats". Medical Science Monitor, 13 (8). http://www.scopus.com/inward/record.url?eid=2-s2.0-34548396344&partnerID=MN8TOARS
Sepodes, B.; Maio, R.; Pinto, R.; Sharples, E.; Oliveira, P.; McDonald, M.; Yaqoob, M.; Thiemermann, C.; Mota-Filipe, H.. 2006. "Recombinant human erythropoietin protects the liver from hepatic ischemia-reperfusion injury in the rat". Transplant International, 19 (11): 919-926. https://doi.org/10.1111/j.1432-2277.2006.00366.x
Sepodes, B.; Maio, R.; Pinto, R.; Marques, C.; Mendes-Do-Vale, J.; McDonald, M.C.; Thiemermann, C.; Mota-Filipe, H.. 2004. "Tempol, an intracelullar free radical scavenger, reduces liver injury in hepatic ischemia-reperfusion in the rat". Transplantation Proceedings, 36 (4): 849-853. https://doi.org/10.1016/j.transproceed.2004.03.050
Pinto, R.; Barrento, C.; Mota-Filipe, H.; Lima, B.S.. 2003. "Phenylephrine Induces Endogenous Noradrenaline Release in the Rat Vas deferens through Nitric Oxide Synthase Pathway". Pharmacology and Toxicology, 93 (4): 191-196. https://doi.org/10.1034/j.1600-0773.2003.930407.x
Pinto, R.; Mota-Filipe, H.; Lima, B.S.. 2002. "Nitric oxide synthase/guanylate cyclase pathway modulates the rat vas deferens contractility induced by phenylephrine". Pharmacology and Toxicology, 91 (4): 179-184. https://doi.org/10.1034/j.1600-0773.2002.910405.x
Mota-Filipe, H.; Sepodes, B.; McDonald, M.; Cuzzocrea, S.; Pinto, R.; Thiemermann, C.. 2002. "The novel PARP inhibitor 5-aminoisoquinolinone reduces the liver injury caused by ischemia and reperfusion in the rat". Medical Science Monitor, 8 (11). http://www.scopus.com/inward/record.url?eid=2-s2.0-0036858375&partnerID=MN8TOARS
Palma, P.; Barata, J. D.; Pinto, R.; Mota-Filipe, H.; Silva-Lima, B.. 2001. "Effect of dietary supplementation with canned Portuguese sardine (cPs) on serum lipids and the glucose metabolic profile in old male rats". Fundamental & Clinical Pharmacology, 15: 96-96. http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000208316200563&KeyUID=WOS:000208316200563
Caneira-da-Silva, M.; Mota-Filipe, H.; Pinto, R.; Albuquerque, L.; Pita, R.; Giao-T-Rico, J. M.. 2001. "Effect of L-NAME on blood pressure, liver injury and renal dysfunction in a rat burn scald injury model". Fundamental & Clinical Pharmacology, 15: 69-69. http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000208316200399&KeyUID=WOS:000208316200399
Pinto, R.; Barrento, C.; Mota-Filipe, H.; Silva-Lima, B.. 2001. "Effect of nitric oxide synthase inhibition in the rat vas deferens contractility and noradrenaline release". Fundamental & Clinical Pharmacology, 15: 85-85. http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000208316200497&KeyUID=WOS:000208316200497
Sepodes, B.; Mota-Filipe, H.; Pinto, R.; McDonald, M. C.; Thiemermann, C.. 2001. "Pretreatment of rats with hemoglobin reduces the multiple organ dysfunction associated with endotoxic shock". Fundamental & Clinical Pharmacology, 15: 85-85. http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000208316200499&KeyUID=WOS:000208316200499
Pinto, R; Vieira, C; Lima, BS. 1999. "Role of N-G-nitro-L-arginine in the rat vas deferens induced contractility by noradrenaline and phenylephrine". British Journal of Pharmacology, 127: U63-U63. http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000081651500117&KeyUID=WOS:000081651500117
Caneira Da Silva, M.D.R.; Mota Filipe, H.; Amaro Pinto, R.M.; Salaverría Timóteo De Carvalho, M.F.; Monteiro Godinho De Matos, M.M.; Cordeiro Ferreira, A.C.; Gião Toscano Rico, J.M.. 1998. "Nitric oxide and human thermal injury short term outcome". Burns, 24 (3): 207-212. https://doi.org/10.1016/S0305-4179(98)00014-X
Pinto, R; Vieira, C; Mota-Filipe, H; Lima, BS. 1998. "Effect of sodium fluoride on the noradrenaline contractility of the rat vas deferens induced". Naunyn-Schmiedebergs Archives of Pharmacology, 358 (1): R258-R258. http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000075207700956&KeyUID=WOS:000075207700956
da Silva, MDC; Filipe, HM; Pinto, RMA; de Carvalho, MFST; de Matos, MMMG; Ferreira, AC; Rico, JMGT. 1998. "Nitric oxide and human thermal injury short term outcome". Burns, 24 (3): 207-212. https://doi.org/10.1016/S0305-4179(98)00014-X
do Rosario Caneira da Silva, M; Mota Filipe, H; Pinto, R M; Salaverria Timoteo de Carval; Godinho de Matos, M M; Cordeiro Ferreira, A; Toscano Rico, J M. 1998. "Nitric oxide and human thermal injury short term outcome.". Burns : journal of the International Society for Burn Injuries, 24 (3): 207-12. http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=MEDLINE&KeyUT=MEDLINE:9677022&KeyUID=MEDLINE:9677022
Vale, F.M.; Castro, M.; Monteiro, J.; Couto, F.S.; Pinto, R.; Rico, J.M.G.T.. 1997. "Acrylic bone cement induces the production of free radicals by cultured human fibroblasts". Biomaterials, 18 (16): 1133-1135. https://doi.org/10.1016/S0142-9612(97)00043-4
Catarino, M; Pinto, R; Conde, A; Costa, A; Soares, J; Tavares, C; DeOliveira, CF; Oliveira, HM. 1997. "Tissue polypeptide specific antigen (TPS) as a complementary test of CA 125 in ovarian cancer". 10th International Meeting of Gynaecological Oncology, 305-309. http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:A1997BH98T00055&KeyUID=WOS:A1997BH98T00055
Caneira, M.; Mota-Filipe, H.; Castro, M.; Pinto, R.; Gondinho-Matos, M.; Cordeiro-Ferreira, A.; Toscano Rico, J.M.. 1996. "Effect of burn blister fluid on the viability of human cultured fibroblasts | Efecto del contenido liquido de las ampollas causadas por quemaduras, en la viabilidad de los fibroblastos humanos". Cirugia Plastica Ibero-Latinoamericana, 22 (3): 231-239.
Caneira, M.; Mota-Filipe, H.; Castro, M.; Pinto, R.; Gondinho-Matos, M.; Cordeiro-Ferreira, A.; Toscano Rico, J.M.. 1996. "Effect of burn blister fluid on the viability of human cultured fibroblasts | Efecto del contenido liquido de las ampollas causadas por quemaduras, en la viabilidad de los fibroblastos humanos". Cirugia Plastica Ibero-Latinoamericana, 22 (3): 231-239. http://www.scopus.com/inward/record.url?eid=2-s2.0-0029946340&partnerID=MN8TOARS
Filipe, P.M.; Freitas, J.P.; Castro, M.; Pinto, R.; Fernandes, A.; de Castro, L.C.; Rico, T.; Rodrigo, F.G.. 1995. "Lipid peroxidation, production of PGE2 and cellular mortality induced by UV in cultured human skin fibroblasts | Peroxydation lipidique, production de PGE2 et mortalité cellulaire induites par les UV dans des fibroblasts cutanés humains en culture.". Comptes rendus des séances de la Société de biologie et de ses filiales, 189 (3): 443-451.
Filipe, P M; Freitas, J P; Castro, M; Pinto, R; Fernandes, A; de Castro, L C; Rico, T; Rodrigo, F G. 1995. "[Lipid peroxidation, production of PGE2 and cellular mortality induced by UV in cultured human skin fibroblasts].". Comptes rendus des seances de la Societe de biologie et de ses filiales, 189 (3): 443-51. http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=MEDLINE&KeyUT=MEDLINE:8521092&KeyUID=MEDLINE:8521092
Filipe, P.M.; Freitas, J.P.; Castro, M.; Pinto, R.; Fernandes, A.; de Castro, L.C.; Rico, T.; Rodrigo, F.G.. 1995. "Lipid peroxidation, production of PGE2 and cellular mortality induced by UV in cultured human skin fibroblasts | Peroxydation lipidique, production de PGE2 et mortalité cellulaire induites par les UV dans des fibroblasts cutanés humains en culture.". Comptes rendus des séances de la Société de biologie et de ses filiales, 189 (3): 443-451. http://www.scopus.com/inward/record.url?eid=2-s2.0-18744428078&partnerID=MN8TOARS
Pinto, Rui. 2019. "Preclinical Study in Vivo for New Pharmacological Approaches in Inflammatory Bowel Disease: A Systematic Review of Chronic Model of TNBS-Induced Colitis". Journal of Clinical Medicine. https://doi.org/10.3390/jcm8101574
Rosa Direito; João Rocha; Ana-Teresa Serra; Adelaide Fernandes; Marisa Freitas; Eduarda Fernandes; Rui Pinto; et al. 2019. "Anti-inflammatory Effects of Persimmon (Diospyros kaki L.) in Experimental Rodent Rheumatoid Arthritis". Journal of Dietary Supplements. https://doi.org/10.1080/19390211.2019.1645256
Rosa Direito; Catarina Reis; Luís Roque; Margarida Gonçalves; Ana Sanches-Silva; Maria Manuela Gaspar; Rui Pinto; et al. 2019. "Phytosomes with Persimmon (Diospyros kaki L.) Extract: Preparation and Preliminary Demonstration of In Vivo Tolerability". Pharmaceutics. https://doi.org/10.3390/pharmaceutics11060296
Rosa Direito; João Rocha; Ana Lima; Maria Margarida Gonçalves; Maria Paula Duarte; Vanessa Mateus; Catarina Sousa; et al. 2019. "Reduction of Inflammation and Colon Injury by a Spearmint Phenolic Extract in Experimental Bowel Disease in Mice". Medicines, 6 (2): 65-65. https://doi.org/10.3390/medicines6020065
Vanessa Mateus; João Estarreja; Inês Silva; Paulo Barracosa; Edite Teixeira-Lemos; Rui Pinto. 2021. "Effect of Cynara cardunculus L. var. altilis (DC) in Inflammatory Bowel Disease". Applied Sciences, 11 (4): 1629-1629. https://doi.org/10.3390/app11041629
Inês Vieira da Silva; Miriam Echevarría; Bárbara P. Soares; Catarina Pimpão; Rui M. A. Pinto; Teresa Costa; João P. B. Freire; et al. 2021. "Glutamine and cystine-enriched diets modulate aquaporins gene expression in the small intestine of piglets". PLOS ONE, 16 (1): e0245739-e0245739. https://doi.org/10.1371/journal.pone.0245739
Mota, A.H.; Duarte, N.; Serra, A.T.; Ferreira, A.; Bronze, M.R.; Custódio, L.; Gaspar, M.M.; et al. 2020. "Further evidence of possible therapeutic uses of sambucus nigra l. Extracts by the assessment of the in vitro and in vivo anti-inflammatory properties of its plga and pcl-based nanoformulations". Pharmaceutics, 12 (12): 1-28. https://doi.org/10.3390/pharmaceutics12121181
Amaro-Leal, Â.; Shvachiy, L.; Pinto, R.; Geraldes, V.; Rocha, I.; Mota-Filipe, H.. 2020. "Therapeutic effects of IkB kinase inhibitor during systemic inflammation". International Immunopharmacology, 84. https://doi.org/10.1016/j.intimp.2020.106509
Amaral, M.; Martins, A.S.; Catarino, J.; Faísca, P.; Kumar, P.; Pinto, J.F.; Pinto, R.; et al. 2020. "How can biomolecules improve mucoadhesion of oral insulin? A comprehensive insight using ex-vivo, in silico, and in vivo models". Biomolecules, 10 (5). https://doi.org/10.3390/biom10050675
Eirini Kalliopi Kydonaki; Laura Freitas; Bruno M Fonseca; HENRIQUE REGUENGO; Carlos; Ana R. Bastos; Emanuel M. Fernandes; et al. 2021. "Bovine Colostrum Supplementation Improves Bone Metabolism in an Osteoporosis-Induced Animal Model". Nutrients. https://doi.org/10.3390/nu13092981
dos Santos Madeira, M.S.M.; Lopes, P.A.A.B.; Martins, C.F.; Assunção, J.M.P.; Alfaia, C.M.R.P.M.; Pinto, R.M.A.; Prates, J.A.M.. 2021. "Dietary Arthrospira platensis improves systemic antioxidant potential and changes plasma lipids without affecting related hepatic metabolic pathways in post-weaned piglets". BMC Veterinary Research, 17 (1). https://doi.org/10.1186/s12917-021-02869-y
Bártolo, I.; Santos, B.S.; Fontinha, D.; MacHado, M.; Francisco, D.; Sepodes, B.; Rocha, J.; et al. 2021. "Spiro-ß-lactam BSS-730A Displays Potent Activity against HIV and Plasmodium". ACS Infectious Diseases, 7 (2): 421-434. https://doi.org/10.1021/acsinfecdis.0c00768
Prates, J.A.M.; Freire, J.P.B.; de Almeida, A.M.; Martins, C.; Ribeiro, D.M.; Osório, H.; Pinho, M.A.S.; et al. 2021. "Influence of dietary supplementation with an amino acid mixture on inflammatory markers, immune status and serum proteome in lps-challenged weaned piglets". Animals, 11 (4). https://doi.org/10.3390/ani11041143
Coelho, D.F.M.; Alfaia, C.M.R.P.M.; Assunção, J.M.P.; Costa, M.; Pinto, R.M.A.; de Andrade Fontes, C.M.G.; Lordelo, M.M.; Prates, J.A.M.. 2021. "Impact of dietary Chlorella vulgaris and carbohydrate-active enzymes incorporation on plasma metabolites and liver lipid composition of broilers". BMC Veterinary Research, 17 (1). https://doi.org/10.1186/s12917-021-02932-8
Kislaya, I.; Gonçalves, P.; Barreto, M.; Sousa, R.D.; Garcia, A.C.; Matos, R.; Guiomar, R.; et al. 2021. "Seroprevalence of SARS-CoV-2 infection in Portugal in May-July 2020: Results of the first national serological survey (ISNCOVID-19),Seroprevalência da infecção por SARS-CoV-2 em Portugal em Maio-Julho de 2020: Resultados do primeiro inquérito serológico nacional (ISNCOVID-19)". Acta Medica Portuguesa, 34 (2): 87-94. https://doi.org/10.20344/amp.15122
Silva, I.; Alípio, C.; Pinto, R.; Mateus, V.. 2021. "Potential anti-inflammatory effect of erythropoietin in non-clinical studies in vivo: A systematic review". Biomedicine and Pharmacotherapy, 139. https://doi.org/10.1016/j.biopha.2021.111558
Pestana, J.M.; Puerta, B.; Santos, H.; Madeira, M.S.; Alfaia, C.M.; Lopes, P.A.; Pinto, R.M.A.; et al. 2020. "Erratum: Impact of dietary incorporation of Spirulina (Arthrospira platensis) and exogenous enzymes on broiler performance, carcass traits, and meat quality (Poultry Science (2020) 99(5) (2519–2532), (S0032579120300195), (10.1016/j.psj.2019.11.069))". Poultry Science, 99 (8): 4100-4100. https://doi.org/10.1016/j.psj.2020.07.001
Pestana, J.M.; Puerta, B.; Santos, H.; Madeira, M.S.; Alfaia, C.M.; Lopes, P.A.; Pinto, R.M.A.; et al. 2020. "Impact of dietary incorporation of Spirulina (Arthrospira platensis) and exogenous enzymes on broiler performance, carcass traits, and meat quality". Poultry Science, 99 (5): 2519-2532. https://doi.org/10.1016/j.psj.2019.11.069
Rocha, J.; Direito, R.; Lima, A.; Mota, J.; Gonçalves, M.; Duarte, M.P.; Solas, J.; et al. 2019. "Reduction of inflammation and colon injury by a Pennyroyal phenolic extract in experimental inflammatory bowel disease in mice". Biomedicine and Pharmacotherapy, 118. https://doi.org/10.1016/j.biopha.2019.109351
Aguiar, P.; Azevedo, O.; Pinto, R.; Marino, J.; Cardoso, C.; Sousa, N.; Cunha, D.; Hughes, D.; Soares, J.L.D.. 2018. "Biomarkers of myocardial fibrosis: Revealing the natural history of fibrogenesis in Fabry disease cardiomyopathy". Journal of the American Heart Association, 7 (6). https://doi.org/10.1161/JAHA.117.007124
Silva, I.; Mendes, P.; Guerra, S.; Pinto, R.; Mateus, V.. 2022. "Anti-Inflammatory Effect of Topiramate in a Chronic Model of TNBS-Induced Colitis". International Journal of Molecular Sciences, 23 (16). https://doi.org/10.3390/ijms23169127
Silva, I.; Correia, R.; Pinto, R.; Mateus, V.. 2022. "Hemin Ameliorates the Inflammatory Activity in the Inflammatory Bowel Disease: A Non-Clinical Study in Rodents". Biomedicines, 10 (8). https://doi.org/10.3390/biomedicines10082025
Modesto, R.; Estarreja, J.; Silva, I.; Rocha, J.; Pinto, R.; Mateus, V.. 2022. "Chemically Induced Colitis-Associated Cancer Models in Rodents for Pharmacological Modulation: A Systematic Review". Journal of Clinical Medicine, 11 (10). https://doi.org/10.3390/jcm11102739
Mateus, V.; Estarreja, J.; Silva, I.; Gonçalves, F.; Teixeira-Lemos, E.; Pinto, R.. 2022. "Effect of Aqueous Extract of Phenolic Compounds Obtained from Red Wine in Experimental Model of Colitis in Mice". Current Issues in Molecular Biology, 44 (6): 2745-2758. https://doi.org/10.3390/cimb44060188
Costa, M.M.; Lopes, P.A.; Assunção, J.M.P.; Alfaia, C.M.R.P.M.; Coelho, D.F.M.; Mourato, M.P.; Pinto, R.M.A.; Lordelo, M.M.; Prates, J.A.M.. 2022. "Combined effects of dietary Laminaria digitata with alginate lyase on plasma metabolites and hepatic lipid, pigment and mineral composition of broilers". BMC Veterinary Research, 18 (1). https://doi.org/10.1186/s12917-022-03250-3
Martins, C.F.; Lopes, P.A.; Palma, M.; Pinto, R.M.A.; Costa, M.; Alfaia, C.M.; Pestana, J.M.; et al. 2022. "Impact of dietary Chlorella vulgaris and feed enzymes on health status, immune response and liver metabolites in weaned piglets". Scientific reports, 12 (1): 16816-16816. https://doi.org/10.1038/s41598-022-21238-9
Coelho, D.; Alfaia, C.M.; Lopes, P.A.; Pestana, J.M.; Costa, M.M.; Pinto, R.M.A.; Almeida, J.M.; et al. 2022. "Impact of Chlorella vulgaris as feed ingredient and carbohydrases on the health status and hepatic lipid metabolism of finishing pigs". Research in Veterinary Science, 144: 44-53. https://doi.org/10.1016/j.rvsc.2022.01.008
Kydonaki, E.K.; Freitas, L.; Reguengo, H.; Simón, C.R.; Bastos, A.R.; Fernandes, E.M.; Canadas, R.F.; et al. 2022. "Pharmacological and Non-Pharmacological Agents versus Bovine Colostrum Supplementation for the Management of Bone Health Using an Osteoporosis-Induced Rat Model". Nutrients, 14 (14). https://doi.org/10.3390/nu14142837
Grácio, M.; Rocha, J.; Pinto, R.; Boavida Ferreira, R.; Solas, J.; Eduardo-Figueira, M.; Sepodes, B.; Ribeiro, A.C.. 2021. "A proposed lectin-mediated mechanism to explain the in Vivo antihyperglycemic activity of ¿-conglutin from Lupinus albus seeds". Food Science and Nutrition, 9 (11): 5980-5996. https://doi.org/10.1002/fsn3.2520
Kydonaki, Eirini; Freitas, Laura; Fonseca, Bruno; Reguengo, Henrique; Simon, Carlos; Bastos, Ana; Canadas, Raphael; et al. 2020. "Bovine colostrum improves bone microstructure in ovariectomized and orchidectomy rats via VEGFA signaling". Journal of Bone and Mineral Research. https://publons.com/wos-op/publon/40693326/
Pinto, R.; Mateus, V.; Centeno, A.; Cardoso, C.; Domingos, C.; Pinto, S.; Pecegueiro, J.. 2019. "Role of the medicine laboratory in the development of new therapeutics: A non-clinical study on the use of erythropoietin in a model of inflammatory bowel disease". Clinica Chimica Acta. https://doi.org/10.1016/J.CCA.2019.03.802
Amorim, Tania; Freitas, Laura; Kydonaki, Eirini K.; Reguendo, Henrique; Simon, Carlos R.; Bastos, Ana R.; Canadas, Raphael F.; et al. 2019. "Bovine Colostrum Supplementation and Bone Health: a Pilot Study". Journal of Bone and Mineral Research. https://publons.com/wos-op/publon/33091847/
2018. "Tubular dysfunction biomarkers in Fabry disease: better than albuminuria to identify patients at risk of nephropathy progression". Molecular Genetics and Metabolism. https://doi.org/10.1016/J.YMGME.2017.12.014
2018. "Collagen type I synthesis biomarkers predict the progression of Fabry disease cardiomyopathy". Molecular Genetics and Metabolism. https://doi.org/10.1016/J.YMGME.2017.12.013
Bartolo, Ines; Diniz, Ana Rita; Borrego, Pedro; Ferreira, Joao Pedro; Bronze, Maria Rosario; Barroso, Helena; Pinto, Rui; et al. 2018. "Evaluation of the fusion inhibitor P3 peptide as a potential microbicide to prevent HIV transmission in women (vol 13, e0195744, 2018)". Plos One. https://doi.org/10.1371/JOURNAL.PONE.0197015
Rocha, J.; Barateiro, A.; Fernandes, A.; Raposo, J.; Direito, R.; Eduardo-Figueira, M.; Pinto, R.; et al. 2013. "GLYCOGEN SYNTHASE KINASE-3 INHIBITION REDUCES LIVER, NEUROMUSCULAR, AND LUNG INJURY CAUSED BY BURN INJURY IN THE RAT". Shock. https://publons.com/wos-op/publon/4010045/
Costa, Ana S. H.; Lopes, Paula A.; Estevao, Marta; Martins, Susana V.; Alves, Susana P.; Pinto, Rui M. A.; Pissarra, Hugo; et al. 2012. "Contrasting Cellularity and Fatty Acid Composition in Fat Depots from Alentejana and Barrosa Bovine Breeds Fed High and Low Forage Diets". International Journal of Biological Sciences. https://doi.org/10.7150/IJBS.8.214
de Lemos, Teixeira E.; Reis, F.; Espinhaco, L.; Baptista, S.; Pinto, R.; Parada, B.; Garrido, P.; et al. 2009. "Low adiponectin levels and paraoxonase activity as markers of oxidative stress and inflammation in atherosclerosis - study in a portuguese population". 9TH CONGRESS OF THE EUROPEAN ASSOCIATION FOR CLINICAL PHARMACOLOGY AND THERAPEUTICS - EACPT. https://publons.com/wos-op/publon/27650436/
Parada, B.; Reis, F.; Teixeira-Lemos, E.; Sereno, J.; Pinto, A. F.; Garrido, P.; Cerejo, R.; et al. 2009. "Inhibition of bladder tumor growth by a cyclooxygenase-2 inhibitor and immunosuppression agents in an experimental study". 9TH CONGRESS OF THE EUROPEAN ASSOCIATION FOR CLINICAL PHARMACOLOGY AND THERAPEUTICS - EACPT. https://publons.com/wos-op/publon/27650438/
Garrido, P.; Reis, F.; de Lemos, Teixeira E.; Costa, E.; Parada, B.; Piloto, N.; Sereno, J.; et al. 2009. "RECOMBINANT HUMAN ERYTHROPOIETIN THERAPY HAS BENEFICIAL CARDIO-RENAL EFFECTS ON MODERATE STAGES OF CHRONIC RENAL FAILURE IN THE RAT". Basic & Clinical Pharmacology & Toxicology. https://publons.com/wos-op/publon/9991534/
Parada, B.; Reis, F.; de Lemos, Teixeira E.; Sereno, J.; Piloto, N.; Cunha, M.; Rocha-Pereira, P.; et al. 2009. "INHIBITION OF BLADDER TUMOR GROWTH BY A CYCLOOXYGENASE-2 INHIBITOR AND IMMUNOSUPPRESSION AGENTS IN AN EXPERIMENTAL STUDY". Basic & Clinical Pharmacology & Toxicology. https://publons.com/wos-op/publon/9991533/
Piloto, N.; Reis, F.; Teixeira, H. M.; Teixeira, de Lemos E.; Parada, B.; Garrido, P.; Sereno, J.; et al. 2009. "RECOMBINANT HUMAN ERYTHROPOIETIN DOPING IN SPORTS - CARDIOVASCULAR EFFECTS IN CHRONIC AND ACUTE AEROBIC EXERCISE IN AN ANIMAL MODEL". Basic & Clinical Pharmacology & Toxicology. https://publons.com/wos-op/publon/9991540/
de Lemos, Teixeira E.; Reis, F.; Espinhaco, L.; Baptista, S.; Pinto, R.; Parada, B.; Garrido, P.; et al. 2009. "LOW ADIPONECTIN LEVELS AND PARAOXONASE ACTIVITY AS MARKERS OF OXIDATIVE STRESS AND INFLAMMATION IN ATHEROSCLEROSIS - STUDY IN A PORTUGUESE POPULATION". Basic & Clinical Pharmacology & Toxicology. https://publons.com/wos-op/publon/11858530/
Marques, Patricia; Rocha, Joao; Pinto, Rui; Sepodes, Bruno; Thiemermann, Christoph; Mota-Filipe, Helder. 2009. "THE EFFECT OF SIMVASTATTN PRE-TREATMENT IN AN EXPERIMENTAL MODEL OF BURN INJURY IN THE RAT". Shock. https://publons.com/wos-op/publon/11850305/
Marques, Patricia; Rocha, Joao; Pinto, Rui; Sepodes, Bruno; Thiemermann, Christoph; Mota-Filipe, Heider. 2009. "THE EFFECT OF LIPOPOLYSACCHARIDE PRECONDITIONING IN AN EXPERIMENTAL MODEL OF BURN INJURY IN THE RAT". Shock. https://publons.com/wos-op/publon/11850306/
Reis, F.; Teixeira-de-Lemos, E.; Espinhaco, L.; Parada, B.; Pinto, R.; Baptista, S.; Dias, A.; Rocha-Pereira, P.; Teixeira, F.. 2008. "PARAOXONASE ACTIVITY, OXIDATIVE STRESS AND HDL-C AND LDL-C LEVELS IN A PORTUGUESE POPULATION SAMPLE". Atherosclerosis Supplements. https://doi.org/10.1016/S1567-5688(08)70333-7
Teixeira de Lemos, E.; Reis, F.; Baptista, S.; Pinto, R.; Sepodes, B.; Vala, H.; Rocha Pereira, P.; Santos Silva, A.; Teixeira, F.. 2008. "PHYSICAL ACTIVITY AS ANTI-INFLAMMATORY THERAPY IN AN ANIMAL MODEL OF TYPE 2 DIABETES". Atherosclerosis Supplements. https://doi.org/10.1016/S1567-5688(08)70398-2
Teixeira, F.; Teixeira de Lemos, E.; Reis, F.; Espinhaco, L.; Baptista, S.; Pinto, R.; Parada, B.; Dias, A.. 2008. "ASSOCIATION BETWEEN ADIPONECTIN, CRP LEVELS AND THE LIPIDIC PROFILE IN A PORTUGUESE POPULATION. A PRELIMINARY STUDY". Atherosclerosis Supplements. https://doi.org/10.1016/S1567-5688(08)70855-9
Sepodes, Bruno; Rocha, Joao; Pinto, Rui; Thiemermann, Christoph; Mota-Filipe, Helder. 2008. "Insulin and TDZD-8, a glycogen synthase kinase-3 beta inhibitor, reduce the liver injury caused by ischemia-reperfusion in the rat". Shock. https://publons.com/wos-op/publon/11850321/
Rocha, Joao; Sepodes, Bruno; Pinto, Rui; Thierermann, Christoph; Mota-Filipe, Helder. 2008. "Simvastatin reduces the liver injury induced by ischemia-reperfusion in the rat". Shock. https://publons.com/wos-op/publon/11850320/
Teixeira, F.; de Lemos, E. Teixeira; Reis, F.; Baptista, S.; Pinto, R.; Sepodes, B.; Vala, H.; Rocha-Pereira, P.; Santos-Silva, A.. 2007. "Exercise training and the inflammatory response in ZDF (type 2) diabetic rats". Atherosclerosis Supplements. https://doi.org/10.1016/S1567-5688(07)71253-9
de Lemos, Edite Teixeira; Reis, Flavio; Baptista, Sofia; Pinto, Rui; Sepodes, Bruno; Vala, Helena; Rocha-Pereira, Petronila; Silva, Alice Santos; Teixeira, Frederico. 2007. "Exercise training is associated with improved levels of C-reactive protein and adiponectin in ZDF (type 2) diabetic rats". Medical Science Monitor. https://publons.com/wos-op/publon/792618/
2007. "Exercise training is associated with improved levels of C-reactive protein and adiponectin in ZDF (type 2) diabetic rats.". Medical Science Monitor. https://publons.com/wos-op/publon/15600746/
Sepodes, Bruno; Rocha, Joao; Marques, Patricia; Pinto, Rui; Thiemermann, Christoph; Mota-Filipe, Helder. 2007. "Inhibition of endogenous hydrogen sulphide formation protects the liver from scald burn injury in the rat". Inflammation Research. https://publons.com/wos-op/publon/11850328/
Sepodes, B.; Rocha, J.; Abdelrahman, M.; Pinto, R.; Oliveira, P.; Thiemermann, C.; Mota-Filipe, H.. 2006. "Inhibition of endogenous hydrogen sulphide formation protects the liver from hepatic ischemia-reperfusion injury in the rat". Shock. https://doi.org/10.1097/00024382-200610001-00049
Sepodes, B.; Abdelrahman, M.; Rocha, J.; Pinto, R.; Mota-Filipe, H.; Thiemermann, C.. 2006. "A glycogen synthase kinase-3 inhibitor (TDZD-8) attenuates the liver and neuromuscular injury caused by burn in the rat". Shock. https://doi.org/10.1097/00024382-200610001-00064
Reto, Marcia; Almeida, Cristina; Barroso, Isabel; Sepodes, Bruno; Pinto, Rui; Mota-Filipe, Helder; Figueira, Maria-Eduardo. 2006. "Hypocholesterolemic effect of green tea and antioxidant effect ofepigallocatechin gallate (EGCG) from green tea". Acta Pharmacologica Sinica. https://publons.com/wos-op/publon/4009973/
Sepodes, Bruno; Abdelrahman, Maha; Pinto, Rui; Figueira, Maria-Eduardo; Mota-Filipe, Helder; Thiemermann, Christoph. 2006. "Glycogen synthase kinase-3b inhibitor, TDZD-8, attenuates the liver injury caused by ischemia-reperfusion in the rat". Acta Pharmacologica Sinica. https://publons.com/wos-op/publon/4009974/
Pinto, Rui; Barrento, Clara; Sepodes, Bruno; Mota-Filipe, Helder; Lima, Beatriz Silva. 2006. "Nitric oxide is involved in the mechanism for the antihypertension action of carvedilol". Acta Pharmacologica Sinica. https://publons.com/wos-op/publon/11850324/
Sepodes, B; Pinto, R; McDonald, M; Eduardo-Figueira, M; Thiemermann, C; Mota-Filipe, H. 2005. "Tyrphostin AG126 reduces ischemia-reperfusion injury of the liver in the rat". Shock. https://publons.com/wos-op/publon/4010034/
Sepodes, B; Pinto, R; McDonald, MC; Thiemermann, C; Mota-Filipe, H. 2004. "Effect of recombinant human erythropoietin in a rat model of ischemia-reperfusion injury of the liver". Shock. https://doi.org/10.1097/00024382-200403001-00346
Pinto, R.; Carvalho, R.; Sepodes, B.; Barrento, C.; Mota-Filipe, H.; Silva-Lima, B.. 2004. "Involvement of nitric oxide synthase pathway and alpha 1-adrenoceptors in the noradrenaline-release induced by phenylephrine in the rat vas deferens". Fundamental & Clinical Pharmacology. https://publons.com/wos-op/publon/11850337/
Sepodes, B.; Pinto, R.; McDonald, M.; Thiemermann, C.; Mota-Filipe, H.. 2004. "The effect of haemoglobin pretreatment on the liver ischaemia/reperfusion injury". Fundamental & Clinical Pharmacology. https://publons.com/wos-op/publon/11850336/
Mota-Filipe H; Sepodes B; McDonald MC; Cuzzocrea S; Pinto R; Thiemermann C. 2002. "The novel PARP inhibitor 5-aminoisoquinolinone reduces the liver injury caused by ischemia and reperfusion in the rat". Medical Science Monitor. https://publons.com/wos-op/publon/15534757/
Palma, P; Barata, JD; Branco, P; Pinto, R; Lima, BS. 2002. "Dietary supplementation with canned sardine (c.s.) improves the parameters of risk of cardiovascular disease. Study in old male rats". British Journal of Pharmacology. https://publons.com/wos-op/publon/11858523/
Pinto, R; Mota-Filipe, H; Barrento, C; Lima, BS. 2002. "Effect of nitric oxide synthase/guanylate cyclase inhibition on the rat vas deferens contractility and noradrenaline efflux". British Journal of Pharmacology. https://publons.com/wos-op/publon/11858522/
Sepodes, B; Pinto, R; McDonald, MC; Mota-Filipe, H; Thiemermann, C. 2002. "Dithiocarbamates attenuate the organ injury and dysfunction caused by endotoxin in the rat". British Journal of Pharmacology. https://publons.com/wos-op/publon/11850333/
Inês Silva; João Solas; Rui Pinto; Vanessa Mateus. 2022. "Chronic Experimental Model of TNBS-Induced Colitis to Study Inflammatory Bowel Disease". International Journal of Molecular Sciences, 23 (9): 4739-4739. https://doi.org/10.3390/ijms23094739
Cristina M. Alfaia; Mónica M. Costa; Rui M. A. Pinto; José M. Pestana; Miguel Mourato; Patrícia Carvalho; Cátia F. Martins; et al. 2022. "Plasma Metabolites and Liver Composition of Broilers in Response to Dietary Ulva lactuca with Ulvan Lyase or a Commercial Enzyme Mixture". Molecules. https://doi.org/10.3390/molecules27217425
